爆发
白喉
白喉棒状杆菌
接种疫苗
医学
背景(考古学)
疫苗可预防疾病
疾病
传染病(医学专业)
环境卫生
免疫
公共卫生
儿科
病毒学
免疫学
地理
病理
抗原
考古
麻疹
作者
Pius Omoruyi Omosigho,Olalekan John Okesanya,Olaniyi Abideen Adigun,Habibi Hassan,Olaleke Noah Olabode,Abioye Sunday Micheal,Usman Abubakar Haruna,Amandeep Singh,Emery Manirambona
出处
期刊:Infectious disorders drug targets
[Bentham Science]
日期:2024-04-01
卷期号:24 (4)
标识
DOI:10.2174/0118715265251299231117045940
摘要
Diphtheria, a vaccine-preventable disease, has resurfaced in Nigeria, where many outbreaks have been reported in recent years. The outbreaks have occurred across the country, including in areas with high vaccination coverage. Corynebacterium diphtheriae, the causal agent, is a highly contagious bacteria that can cause severe respiratory and systemic symptoms and can be fatal if not treated. The reemergence of diphtheria in Nigeria is most likely due to a combination of factors, including gaps in routine immunization regimens. The outbreak is further aggravated by multiple epidemics, which have diverted resources and attention away from the emergency of other infectious diseases. Furthermore, there is a lack of awareness of diphtheria in Nigeria. With a focus on the difficulties in controlling the disease, methods of diagnosis, available treatments, and preventive measures, this study provides a thorough analysis of diphtheria, covering its historical context, clinical presentation, associated complications, and current outbreaks. It emphasizes how important vaccination, early detection, and better access to healthcare are in reducing diphtheria outbreaks. The study highlights the serious effects of diphtheria on public health, particularly in regions with scarce resources and vaccine resistance, and offers a number of suggestions to overcome these challenges and prevent further outbreaks.
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