Authors' reply to letter: He who controls Clostridia and Bacteroidia controls the gut microbiome: The concept of targeted probiotics to restore the balance of keystone taxa in irritable bowel syndrome

微生物群 梭状芽孢杆菌 肠易激综合征 医学 生物 生物信息学 胃肠病学 遗传学 细菌
作者
Benjamin H. Mullish,D. R. Michael,Maya Dabcheva,Thomas S. Webberley,Nathan Coates,D. A. John,Duolao Wang,Yan Luo,Sue Plummer,Julian R. Marchesi
出处
期刊:Neurogastroenterology and Motility [Wiley]
卷期号:36 (8)
标识
DOI:10.1111/nmo.14820
摘要

Neurogastroenterology & MotilityEarly View e14820 LETTER TO THE EDITOR Authors' reply to letter: He who controls Clostridia and Bacteroidia controls the gut microbiome: The concept of targeted probiotics to restore the balance of keystone taxa in irritable bowel syndrome B. H. Mullish, Corresponding Author B. H. Mullish [email protected] orcid.org/0000-0001-6300-3100 Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK Correspondence B. H. Mullish, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, St Mary's Hospital Campus, Imperial College London 10th Floor, QEQM Wing, South Wharf Road, Paddington, London W2 1NY, UK. Email: [email protected]Search for more papers by this authorD. R. Michael, D. R. Michael Cultech Limited, Port Talbot, UKSearch for more papers by this authorM. Dabcheva, M. Dabcheva Clinical Research Unit, MC Comac Medical, Sofia, BulgariaSearch for more papers by this authorT. S. Webberley, T. S. Webberley Cultech Limited, Port Talbot, UKSearch for more papers by this authorN. Coates, N. Coates Cultech Limited, Port Talbot, UKSearch for more papers by this authorD. A. John, D. A. John Cultech Limited, Port Talbot, UKSearch for more papers by this authorD. Wang, D. Wang Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UKSearch for more papers by this authorY. Luo, Y. Luo Mailman School of Public Health, Columbia University Medical Centre, New York, New York, USASearch for more papers by this authorS. F. Plummer, S. F. Plummer Cultech Limited, Port Talbot, UKSearch for more papers by this authorJ. R. Marchesi, J. R. Marchesi Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UKSearch for more papers by this author B. H. Mullish, Corresponding Author B. H. Mullish [email protected] orcid.org/0000-0001-6300-3100 Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK Correspondence B. H. Mullish, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, St Mary's Hospital Campus, Imperial College London 10th Floor, QEQM Wing, South Wharf Road, Paddington, London W2 1NY, UK. Email: [email protected]Search for more papers by this authorD. R. Michael, D. R. Michael Cultech Limited, Port Talbot, UKSearch for more papers by this authorM. Dabcheva, M. Dabcheva Clinical Research Unit, MC Comac Medical, Sofia, BulgariaSearch for more papers by this authorT. S. Webberley, T. S. Webberley Cultech Limited, Port Talbot, UKSearch for more papers by this authorN. Coates, N. Coates Cultech Limited, Port Talbot, UKSearch for more papers by this authorD. A. John, D. A. John Cultech Limited, Port Talbot, UKSearch for more papers by this authorD. Wang, D. Wang Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UKSearch for more papers by this authorY. Luo, Y. Luo Mailman School of Public Health, Columbia University Medical Centre, New York, New York, USASearch for more papers by this authorS. F. Plummer, S. F. Plummer Cultech Limited, Port Talbot, UKSearch for more papers by this authorJ. R. Marchesi, J. R. Marchesi Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UKSearch for more papers by this author First published: 19 May 2024 https://doi.org/10.1111/nmo.14820Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1Sitkin S, Pokrotnieks J. He who controls Clostridia and Bacteroidia controls the gut microbiome: the concept of targeted probiotics to restore the balance of keystone taxa in irritable bowel syndrome. Neurogastroenterol Motil. 2024. https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.14805 PubMedWeb of Science®Google Scholar 2Mullish BH, Michael DR, Dabcheva M, et al. A double-blind, randomized, placebo-controlled study assessing the impact of probiotic supplementation on the symptoms of irritable bowel syndrome in females. Neurogastroenterol Motil. 2024; 36(4):e14751. doi:10.1111/NMO.14751 10.1111/nmo.14751 CASPubMedWeb of Science®Google Scholar 3 ISRCTN–ISRCTN90136957: Can taking probiotics ("friendly" bacteria) reduce upper respiratory tract infections in healthcare workers? Accessed April 18, 2024 https://www.isrctn.com/ISRCTN90136957?q=90136957&filters=&sort=&offset=1&totalResults=1&page=1&pageSize=10 Google Scholar 4Mullish BH, Michael DR, Webberley TS, et al. The gastrointestinal status of healthy adults: a post hoc assessment of the impact of three distinct probiotics. Benefic Microbes. 2023; 14(3): 183-195. doi:10.3920/BM2022.0092 10.3920/BM2022.0092 Web of Science®Google Scholar 5John D, Michael D, Dabcheva M, et al. A double-blind, randomized, placebo-controlled study assessing the impact of probiotic supplementation on antibiotic induced changes in the gut microbiome. Front Microb. 2024; 3:1359580. doi:10.3389/FRMBI.2024.1359580 10.3389/frmbi.2024.1359580 Google Scholar 6Mars RAT, Yang Y, Ward T, et al. Longitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome. Cell. 2020; 182(6): 1460-1473.e17. doi:10.1016/J.CELL.2020.08.007 10.1016/j.cell.2020.08.007 CASPubMedWeb of Science®Google Scholar 7Han L, Zhao L, Zhou Y, et al. Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity. ISME J. 2022; 16(4): 983-996. doi:10.1038/s41396-021-01123-5 10.1038/s41396-021-01123-5 CASPubMedWeb of Science®Google Scholar 8Mullish BH, Michael DR, McDonald JAK, Masetti G, Plummer SF, Marchesi JR. Identifying the factors influencing outcome in probiotic studies in overweight and obese patients: host or microbiome? Gut. 2021; 70(1): 225-226. doi:10.1136/gutjnl-2020-321110 10.1136/gutjnl-2020-321110 PubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issuee14820 ReferencesRelatedInformation

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