组分(热力学)
瓶颈
超分子化学
化学
控制(管理)
计算机科学
生化工程
过程(计算)
机制(生物学)
材料科学
组合化学
工艺工程
纳米技术
分子
工程类
有机化学
人工智能
物理
哲学
认识论
嵌入式系统
操作系统
热力学
作者
Yantao Yang,Ye-Qin Tao,Wenhan Tang,Sen Li,Jiafu Shi,Yiqun Zhou,Wenlong Liu,Fang He
出处
期刊:China journal of Chinese materia medica
[China Journal of Chinese Materia Medica]
日期:2016-12-15
被引量:1
标识
DOI:10.4268/cjcmm20162430
摘要
Controlled sustained-release preparation (CSRP) is a definitely important source of innovative medicines, however, its further researches and development are limited due to the complexity of Chinese medicine (CM) compositions, and a series of unclear key problems like the apparent properties from physical and chemical aspects. Combined with the CM characteristics of the multiple components and synergistic effect, a series of bottleneck problems in the preparation of CSRP were analyzed. Then the mechanism and influences of supermolecular chemical theory in the CSRP about the multiple-components overall-control were explored under the guideline of "overall control, synchronous dissolution" in CSRP, based on the previous explications about supramolecular chemistry theories and with the application of single component precision controlling technologies. The supermolecular mechanism of multi-component overall control and synchronous release of the CSRP was investigated, providing an useful academic reference for the research and development of the CSRP and laying the theoretical and technical foundation for the manufacturing process of CSRP.
科研通智能强力驱动
Strongly Powered by AbleSci AI