The central importance of conceptualization has been widely recognized. Existing practices of conceptualization in the information systems discipline are yet in their genesis. This paper first discusses confusion around the notion of “conceptualization”; by drawing from the philosophy of science literature, we examine the scientific basis of conceptualization and advocate for the importance of construct clarity in conceptualization practice. Previous methodological literature paid scant attention to the conduct of conceptualization. Hence, in order to counsel researchers on how to conduct conceptualization, this paper develops a set of actionable guidelines for researchers to engage more deeply with conceptualization.