Congo red dye is majorly used in histological staining and it has a major role to play in microbial screening.More significant use of congo red lies in microbial screening of cellulose predominantly carboxymethy cellulose.The major objective of this study is to avail the dye in microbial screening to identify the zone of clearance certain fungal species. After the microbial screening and incubation there was a color change in the fungal grown areas when treated with congo red dye.Thus the congo red dyes cromogenic effect can be assessed from this experiment.