Enhanced Expression of Dermal Aquaporins by Polysaccharide from Camellia sinensis

Enhanced Expression of Dermal Aquaporins by Polysaccharide from Camellia sinensisThe green tea polysaccharide was extracted from leaves of Camellia sinensis and hydrolyzed with enzyme.Skin moisturization effect of green tea polysaccharide was studied with 2D-PAGE analysis of epidermal hydration factors.Among up-regulated proteins extracted from Hacat cell treated with Green tea polysaccharide on 2DE gel, 5 aquaporins were observed.Among them the aquaporin 5 and 8 were increased 3.4 and 5.3 times respectively.The green tea polysaccharide was found to be effective for skin moisturization by enhanced expression of aquaporins.