Objective To study the postliposuction histologic alterations of adipose tissue in Mini-pigs. Methods Five Wuzhishan adult Mini pigs were suctioned with syringe assisted liposuction using a suction needle of 2 mm in diameter. The subcutaneous adipose tissues on both operated and controlled non operated areas were collected from one week to eight months after operation and all samples were measured and observed macroscopically and microscopically. Results The thickness of subcutaneous adipose tissues at the operated sites is thinner than the controlled sites. There was no significant difference in adipocyte morphology between the two kinds of samples. The structure of fat tissue recovered normally during 6~8 months after liposuction. Conclusion Liposuction is an effective operation to eliminate the subcutaneous adipose tissue and the structure of subcutaneous adipose tissue is completely normal in 6~8 months after the operation.;