Considering the outside disturbances and the system nonlinear parameter perturbations,the design of robust H∞ controller is studied for a class of neutral system with time-delay based on Lyapunov stability theory.Using the linear matrix inequality(LMI) method,the robust H∞ controller for a class of neutral system with time-delay and uncertain nonlinear perturbations is designed.A sufficient condition for such systems is presented,and the robust H∞ controller is obtained.The simulation result shows that the controller has overcome the outside disturbances and system nonlinear parameter perturbations.The H∞ performance of closed-loop system is perfectly realized,so the proposed controller is effective.