Review on Lipid-Lowing Effects by Polysaccharide

高脂血症是体内脂质代谢紊乱导致血脂水平增高，并由此引发一系列临床病理表现的病症。饮食不节等可导致机体功能减弱或失调，脂质代谢紊乱，发生高脂血症。研究表明高脂血症最主要、最直接的损害是加速全身动脉粥样硬化，是心血管疾病最重要的危险因素之一，同时与中风、糖尿病、高血压、脂肪肝等疾病有着密切关系。因此，有效降低血脂是目前临床研究的热点之一。多糖是重要的生物高分子化合物，是构成生命的四大基本物质之一。研究证实多糖具有降血脂作用，本文就多糖降血脂作用的研究进展进行简要概述。 Hyperlipidemia is a lipid metabolic disorder with increased blood lipid level in the body, which results in a series of clinical symptoms. Improper diet and other factors can cause body dysfunc-tion and imbalance, which lead to lipid metabolic disorder and hyperlipidemia. Research shows that the direct injury of hyperlipidemia is to accelerate systemic atherosclerosis and is one of the risk factors for cardiovascular diseases. Hyperlipidemia has been shown to relate to stroke, diabetes, hypertension and fatty liver. Thus, how to effectively reduce lipid level is one of most important clinical problems. Polysaccharide is an important biological macromolecular com-pound and one of the four basic substances for life. It has been proved that polysaccharide has lipid-lowing effects. This review will make a brief introduction on lipid-lowering effect of polysaccharide.