奥拉帕尼
医学
卵巢癌
生殖系
肿瘤科
内科学
种系突变
BRCA突变
突变
癌症
聚ADP核糖聚合酶
遗传学
基因
生物
聚合酶
作者
Andrés Poveda,Stéphanie Lheureux,Nicoletta Colombo,David Cibula,Mari Elstrand,Johanne I. Weberpals,Maria Bjurberg,Ana Oaknin,Magdalena Sikorska,Antonio González‐Martín,Radosław Mądry,M.J. Rubio Pérez,Jonathan A. Ledermann,Ignacio Romero,Ozan Özgören,Alan Barnicle,Helen Marshall,Zahid Bashir,Erik Škof
标识
DOI:10.1016/j.ygyno.2025.04.580
摘要
These data provide additional evidence of olaparib as maintenance therapy in patients with non-gBRCAm platinum-sensitive relapsed ovarian cancer, with longer OS observed in those with HRD-positive tumors. The safety profile was consistent with the primary analysis and known safety profile of olaparib, with no new safety findings.
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