Ferrocene-functionalized COF-derived Fe single-atom dispersed N-doped porous carbon for enhanced electrochemical sensing of chloramphenicol

Fe single-atom dispersed N-doped porous carbon (FeSA-NC) was synthesized using a ferrocene-functionalized covalent organic framework as the precursor. Experimental and theoretical results revealed that FeSA-NC possessed excellent catalytic activity and conductivity, enabling high-performance electrochemical sensing of chloramphenicol (CAP). The successfully CAP detection in milk, honey and tap water proved its practicability.