Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy

Munronin V (1), a limonoid possessing a newly 7/7/6 tricarbocyclic framework, was obtained from Munronia henryi Harms. 1 inhibited Tau pathology by activating TFEB-mediated autophagy, suggesting its potential for against Alzheimer's disease (AD).