医学
肌腱病
富血小板血浆
体外冲击波疗法
肩袖
上髁炎
肌腱
肌肉骨骼痛
肌筋膜疼痛综合征
康复
物理疗法
外科
病理
内科学
血小板
替代医学
肘部
作者
Nourhan Elsayed Shamseldeen,Mohammed Hegazy,Nadia Abdalazeem Fayaz,Nesreen Fawzy Mahmoud
出处
期刊:World journal of orthopedics
[Baishideng Publishing Group Co (World Journal of Orthopedics)]
日期:2023-07-18
卷期号:14 (7): 572-581
被引量:1
标识
DOI:10.5312/wjo.v14.i7.572
摘要
Shoulder pain is a common musculoskeletal complaint, and rotator cuff (RC) pathologies are one of the main causes. The RC undergoes various tendinopathic and avascular changes during the aging process. Other degenerative changes affecting its healing potential make it an appealing target for biological agents. Platelet-rich plasma (PRP) has demonstrated the potential to deliver a high concentration of several growth factors and anti-inflammatory mediators, and its clinical use is mainly supported by experiments that demonstrated its positive effect on muscle, ligaments, and tendinous cells. This review aimed to specify the role of PRP and its future applications in RC tendinopathies based on the current clinical evidence. Due to the different characteristics and conflicting outcomes, clinicians should use PRP with moderate expectations until more consistent evidence is available. However, it is reasonable to consider PRP in patients with contraindications to corticosteroid injections or those with risk factors for inadequate healing. Its autologous origin makes it a safe treatment, and its characteristics make it a promising option for treating RC tendinopathy, but the efficacy has yet to be established.
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