啮齿动物模型
啮齿动物
药理学
医学
主动脉瘤
化学
主动脉
内科学
生物
生态学
作者
Yongzhen Wei,Huan Jiang,Fengjuan Li,Chao Chai,Yaping Xu,Mengmeng Xing,Weiliang Deng,He Wang,Yuexin Zhu,Sen Yang,Yongquan Yu,Wenming Wang,Yan Wei,Yu Guo,Jinwei Tian,Jie Du,Z. Guo,Yuan Wang,Qiang Zhao
标识
DOI：10.1126/scitranslmed.adh1763
摘要
An abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. We identified plasma insulin-like growth factor 1 (IGF1) as an independent risk factor in patients with AAA by correlating plasma IGF1 with risk. Smooth muscle cell- or fibroblast-specific knockout of
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