自噬
细胞生物学
化学
泛素
生物
溶酶体
细胞
细胞培养
抗体
免疫系统
分子生物学
作者
Yaqin Tian,Liting Lu,Shuhui Wang,Jingwen Zhang,Mei Xue,Jiumeng Sun,Ying Shao,Zhengyu Wang,Mengling Peng,Jian Tu,Xiangjun Song
标识
DOI:10.1080/03079457.2026.2717141
摘要
RESEARCH HIGHLIGHTS: APEC Hcp2b protein translocates into HD11 cells and induces significant cytotoxicity.Hcp2b elicits incomplete autophagy, characterized by blocked autophagic flux.Proteomic analysis demonstrated Hcp2b impairs lysosomes, blocking autophagy.
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