生育率
医学
内科学
内分泌学
霍奇金淋巴瘤
肿瘤科
临床研究阶段
强的松
丙卡巴嗪
保持生育能力
激素
促黄体激素
化疗
卵巢
生物
性腺激素
功能(生物学)
性腺
化疗方案
作者
A. S. Robertz,Ina Bühnen,Julia Meissner,Karolin Trautmann-Grill,Peter Herhaus,Teresa Halbsguth,Valdete Schaub,Andrea Kerkhoff,Stephan Mathas,Matthias Bormann,Andreas Dickhut,Christian Jaworek,Michael Fuchs,Carsten Kobe,Christian Baues,P Borchmann,Bastian von Tresckow,Karolin Behringer,Paul J Bröckelmann
出处
期刊:Blood
[Elsevier BV]
日期:2026-04-02
标识
DOI:10.1182/blood.2025031809
摘要
In 82 patients with classic Hodgkin lymphoma, stable gonadal hormone levels were observed up to 24 months after nivolumab and AVD (N-AVD) first-line treatment in the NIVAHL trial. These findings suggest preserved gonadal function and fertility following 4×N-AVD. NCT03004833.
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