植物化学
亚麻
化学
生物活性
生物分子
药物发现
药用植物
传统医学
植物
立体化学
生物
生物化学
体外
医学
作者
Rajiv Dahiya,Sunita Dahiya,Jyoti Priyadarshini Shrivastava,Neeraj Kumar Fuloria,Hemendra Gautam,Rita Mourya,Shivkanya Fuloria
标识
DOI:10.1002/ardp.202000446
摘要
Cyclopolypeptides are among the most predominant biomolecules in nature, especially those derived from plant seeds. This category of compounds has gained extraordinary attention due to remarkable variety of structures and valuable biofunctions. These congeners display enormous variation in terms of both structure and function and are the most significant biomolecules due to their widespread bioproperties. The estrogenic activity, immunosuppressive activity, cytotoxicity, vasorelaxant activity, and other properties possessed by cyclic peptides from seeds of plants make these congeners attractive leads for the drug discovery process. The current study covers the important structural features, structure–activity relationship, synthesis methods, and bioproperties of plant seeds-originated bioactive peptides from Vaccaria segetalis, Linum usitatissimum, and Goniothalamus leiocarpus, which may prove vital for the development of novel therapeutics based on a peptide skeleton.
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