神经科学
脑干
背景(考古学)
连接体
生物神经网络
神经元回路
中心图形发生器
脊髓
心理学
生物
医学
功能连接
内科学
节奏
古生物学
作者
Roberto Leiras,Jared M. Cregg,Ole Kiehn
出处
期刊:Annual Review of Neuroscience
[Annual Reviews]
日期:2022-07-08
卷期号:45 (1): 63-85
被引量:49
标识
DOI:10.1146/annurev-neuro-082321-025137
摘要
Locomotion is a universal motor behavior that is expressed as the output of many integrated brain functions. Locomotion is organized at several levels of the nervous system, with brainstem circuits acting as the gate between brain areas regulating innate, emotional, or motivational locomotion and executive spinal circuits. Here we review recent advances on brainstem circuits involved in controlling locomotion. We describe how delineated command circuits govern the start, speed, stop, and steering of locomotion. We also discuss how these pathways interface between executive circuits in the spinal cord and diverse brain areas important for context-specific selection of locomotion. A recurrent theme is the need to establish a functional connectome to and from brainstem command circuits. Finally, we point to unresolved issues concerning the integrated function of locomotor control.
科研通智能强力驱动
Strongly Powered by AbleSci AI