Visible‐Light‐Promoted Transition‐Metal‐Free Approach toward Phosphoryl‐Substituted Dihydroisoquinolones via Cascade Phosphorylation/Cyclization of N‐Allylbenzamides

Abstract A transition‐metal‐free visible‐light‐promoted radical phosphorylation/cyclization of N ‐allylbenzamides with phosphine oxides for the synthesis of phosphoryl‐substituted dihydroisoquinolones was developed under room temperature. This protocol features mild reaction conditions, simple operation, broad substrate scope as well as scale‐up ability. magnified image