Objective To study the stabilization effect of β-cyclodextrin inclusion on Stilbene Glycoside(THSG).Methods The β-cyclodextrin inclusion of THSG was prepared by solution method.After verified with TG-DTA and UV spectrometry,the stability of the inclusion was researched at pH 1.2,4.9,6.8 and under irradiation and compared with THSG.Results The ratio of inclusion was 1:1.Both THSG and its β-cyclodextrin inclusion were stable at pH 1.2,meanwhile stabilization effect of β-cyclodextrin inclusion on THSG can be discovered at pH 4.9,6.8 and under irradiation.Conclusion The stability of THSG can be obviously improved by β-cyclodextrin inclusion.