Study on the Regulation of Dynamic Accumulation of the Effective Components of Coptis chinensis

Objective To study the dynamic accumulation regulation of the effective components of Coptis chinensis,so to provide the experimental data of optimal harvest time of Coptis chinensis.Methods The samples of two to five years were gathered from the same glebe and time.Berberine and the total alkaloids were analyzed by HPLC and UV methods.Results The dynamic accumu- lation of effective components in the rootstalk of the Coptis chinensis had regularity in the certain extend.The contents of berberine in samples were almost the lowest in April in every year,which were mostly the highest in October and November from the samples grown 4～5 years,but the content of the component was mostly the highest in 5-year-old Coptis chinensis in the series samples. The content of the total alkaloids increased year by year in the rootstalk of the Coptis chinensis,which was mostly the highest in October and November in every year,but the content of the component was mostly the highest in 5-year-old Coptis chinensis in the samples.Conclusion According to the accumulation pattern of the effective components in the Coptis chinensis,the optimal harvest time is from September to November.