Phylogenetic Analysis of 25 SIV/HIV Isolates Sequences

16 SIV and 9 HIV isolates were selected for phylogenetic analysis,with HTLV-1 as an outgroup.CLUSTAL X,PHYLIP and MEGA were used to analysis the genomes and the sequences of Env,Gag,Pol.The phylogenetic trees were constructed by the Neighbor-Joining(N-J) method and Maximum Likelihood(ML) method.The results confirmed that the two clusters of HIV were closely related to the two clusters of SIV.HIV-1 was highly related to several subtypes of SIVcpz and HIV-2 was highly related to SIVsm and SIVmm.