The expression of Staphylococcus epidermidis biofilm in patients with chronic rhinosinusitis

Objective To investigate the expression of Staphylococcus epidermidis biofilm in the nasal mucosa of patients with chronic rhinosinusitis(CRS).Methods 180 samples were collected during endoscopic sinus surgery from patients with CRS.According to the results of bacterial culture,they were classified into 4 groups [Staphylococcus epidermidis growth group(79 cases),other Staphylococcus aureus growth group(33 cases),negative bacillus growth group(27 cases) and bacterial culture-negative group(41 cases)].All samples were subjected to scanning electron microscopy.Results The scanning electron microscopy analysis showed bacterial biofilms in all cases of the Staphylococcus epidermidis growth group,and the expressions for the 4 groups were 100%(79/79),75.8%(25/33),77.8%(21/27) and 41.5%(17/41),respectively.The results were compared between Staphylococcus epidermidis growth group and other 3 groups(P0.01).Conclusions Staphylococcus epidermidis is important for the formation of biofilms in the patients with CRS.