Treatment of Children with ADHD and Tic Disorders

Treatment of children with attention deficit hyperactivity disorder (ADHD) and chronic tic disorders has been complicated by fears that methylphenidate (MPH [ritalin]) and other stimulants may exacerbate tics in approximately 20% of children. In a multisite, randomized, double-blind, placebo-controlled trial, 136 children aged 7 to 14 years with ADHD and chronic tic disorders were assigned to clonidine …