Rhodium-catalyzed C2 and C4 C–H activation/annulation of 3-(1H-indol-3-yl)-3-oxopropanenitriles with internal alkynes: a facile access to substituted and fused carbazoles

Rhodium-catalyzed C2 and C4 C–H activation/annulation of 3-(1H-indol-3-yl)-3-oxopropanenitriles with internal alkynes has been developed. Substituted and fused carbazole derivatives were obtained through formal rhodium-catalyzed (4+2) or tandem (4+2) and (5+2) cycloaddition reactions under mild reaction conditions in good yields.