医学
皮肌炎
结缔组织
组织病理学
吗啡
病理
皮肤病科
结缔组织病
混合性结缔组织病
疾病
硬皮病(真菌)
活检
自身免疫性疾病
接种
作者
Alvaro C. Laga,Allison R. Larson,Scott R. Granter
标识
DOI:10.1016/j.path.2017.01.012
摘要
Connective tissue disorders (CTDs), also known as collagen vascular diseases, are a heterogeneous group of diseases with a common pathogenic mechanism: autoimmunity. Precise classification of CTDs requires clinical, serologic, and pathologic correlation and may be difficult because of overlapping clinical and histologic features. The main contribution of histopathology in the diagnosis of these disorders is to confirm, rule out, or alert clinicians to the possibility of CTD as a disease category, rather than producing definitive diagnoses of specific entities. This article discusses the histopathologic spectrum of 3 common rheumatologic skin disorders: lupus erythematosus, dermatomyositis, and morphea (localized scleroderma).
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