Simultaneous Determination of Hydrochlorothiazide and its Impurities (Chlorothiazide and Salamide) in a Quaternary Mixture with Candesartan Cilexetil by HPTLC Method

Introduction: No methods were reported for the simultaneous determination of HCZ and CAN in the presence of CHL and DSA; accordingly, the aim of the presented research work is to provide highly selective, accurate and simple HPTLC method for the determination of the proposed mixture in pure forms and dosage form. Keywords: Validation, densitometry, hydrochlorothiazide, candesartan cilexetil, chlorothiazide, salamide.