角化过度
疥疮
皮肤病科
入射(几何)
侵染
医学
生物
植物
光学
物理
作者
Gaëlle Jouret,R. Bounemeur,A. Presle,Romulus Takin
标识
DOI:10.1016/j.annder.2016.02.001
摘要
Crusted scabies is a rare and severe form of infestation by Sarcoptes scabies var. hominis. It is characterized by profuse hyperkeratosis containing over 4000 mites per gram of skin, with treatment being long and difficult. The condition is both direct and indirectly contagious. It has a central role in epidemic cycles of scabies, the incidence of which is on the rise in economically stable countries. Recent discoveries concerning the biology of mites, the pathophysiology of hyperkeratosis and the key role of IL-17 in this severe form open up new therapeutic perspectives.
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