Concise and Facile Synthesis of Novel Pyrano[2,3-d]pyrimidine-7- one/thione Derivatives as In Vitro Antimicrobial and Antitubercular Agents

Inspired by the broad bio-activity of pyran and pyrimidine based heterocyclic compounds, novel 5-amino-4- Keywords: Pyrimidone, Pyrimidine thione, Pyranopyrimidine, Antimicrobial activity, Antitubercular activity, Mycobacterium Tuberculosis H37Rv, facile synthesis, glabrachromene, thiazolopyrimidine, absorption bands, IR spectrum, 1H NMR, Staphylococcus aureus, Streptococcus pyogenes, Lowenstein-Jensen medium