Clinical study of early use of dehydration therapy with severe tendency of hand foot and mouth disease

Objective : To investigate new ways and new measures to treat foot and mouth disease, to reduce the occurrence of severe cases, thereby reducing the mortality. Methods : Using double blind, control group randomly selected cases, treated with mannitol plus routine treatment, the control group with conventional therapy. Results : the group of mannitol plus routine treatment all discharged, and no cases were converted into severe cases, while the half of the control group were converted into severe cases, plus mannitol after remission and cured, and the control group was significantly prolonged duration of about 10 days. Conclusion : We believe that children with tendency of hand foot and mouth disease should be treated with mannitol in the early period. It can reduce hospitalization time and prevent hand foot and mouth disease development so that the case fatality rate is greatly reduced, and it is worthy of popularization and application.