By using temperature suitability model, this paper calculated, evaluated, and predicted the temperature suitability and its spatiotemporal differences of Cinnamomum camphora in subtropical China between 1960 and 2005. Spatially, the temperature suitability of C. camphora could be divided into four areas, i.e., high suitability, suitability, low suitability, and no suitability. In eastern subtropics, the temperature suitability of C. camphora decreased gradually from south to north; while in western subtropics, there was a large area of no suitability. Temporally, the temperature suitability of C. camphora had an increasing trend over time, and the area of temperature suitability was expanding northward. The analysis of the trend rate and variability of the temperature suitability showed that C. camphora was more suitable to be planted in southern subtropics and not suitable in western subtropics, and would be suitable in northern subtropics.