Basic Research of Panax Notoginseng Saponins in Clinical Application

Panax notoginseng has a unique feature of controlling bleeding without leaving stasis,eliminating stasis without negatively affecting body function. Panax notoginseng has been widely used in various kinds of internal and external bleeding in clinical practice and frequently adopted in the treatment of cardiovascular diseases,cancer and hematological disorders. Panax notoginseng's major chemical components are: Panax notoginseng saponins( PNS),dencichine,Panax polysaccharides,flavonoid glycosides,volatile oils,amino acids and various trace elements,etc. PNS is as one of the effective components of Panax notoginseng and its related pharmacological preparations have been extensively used in clinic. The current review summarizes the recent progress on the basic research and associated clinical applications of preparations of PNS.