Therapeutic efficiency of topiramate alone and co-administration in children epilepsy

topiramate was used in 69 children with newly diagnosed epilepsy or as supplementary therapy for those poorly controlled patients frequency of after full dose toprimate was studied based on episode 3 month before topiramate therapy or ≥2 times episode patients and then calculate effective percentage. The total effectiveness of topiramate for childhood epilepsy is 85.5% with 56.5% in topiramate use alone and 52.2% in those of topiramate supplement therapy. There is 33.3% cases.in minor manifestation except 2 with frequent onset. Topiramate may be used as a first line drug for childhood epilepsy for its effectiveness and safety.