Synthesis of 1H-1,5-Benzodiazepin-2(3H)-ones from 5(4H)-Isoxazolone, a Heterocyclic Bifunctional C-3 Synthon

All articles of this category Unsubstituted and 7- or 8-substituted 4-aryl-1 H -1,5-benzodiazepin-2(3 H )-ones 3a-t have been synthesized by the condensation of 3-aryl-5(4 H )-isoxazolones 1a-e and parent 4-substituted 1,2-benzenediamines 2a-d under acidic conditions.