材料科学
介孔材料
化学工程
球体
布洛芬
药物输送
介孔二氧化硅
纳米技术
纳米颗粒
毒品携带者
有机化学
医学
化学
物理
天文
工程类
药理学
催化作用
作者
Wenru Zhao,Hangrong Chen,Yongsheng Li,Liang Li,Meidong Lang,Jianlin Shi
标识
DOI:10.1002/adfm.200701317
摘要
Abstract A novel kind of rattle‐type hollow magnetic mesoporous sphere (HMMS) with Fe 3 O 4 particles encapsulated in the cores of mesoporous silica microspheres has been successfully fabricated by sol–gel reactions on hematite particles followed by cavity generation with hydrothermal treatment and H 2 reduction. Such a structure has the merits of both enhanced drug‐loading capacity and a significant magnetization strength. The prepared HMMSs realize a relatively high storage capacity up to 302 mg g −1 when ibuprofen is used as a model drug, and the IBU–HMMS system has a sustained‐release property, which follows a Fick's law.
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