诱导多能干细胞
心肌梗塞
移植
梗塞
心脏病学
医学
干细胞
细胞
内科学
神经科学
胚胎干细胞
生物
细胞生物学
遗传学
生物化学
基因
作者
Hideki Kobayashi,Hajime Ichimura,Nobuhiko Ohashi,Yuji Shiba
出处
期刊:Methods in molecular biology
日期:2021-01-01
卷期号:: 295-302
被引量:1
标识
DOI:10.1007/978-1-0716-1484-6_25
摘要
Recent evidence has provided exciting proof of concepts for the use of pluripotent stem cell-derived cardiomyocytes (PSC-CMs) for cardiac repair; however, large animal studies, which better reflect human disease, are required for clinical application. Here, we describe how to create myocardial infarction in cynomolgus monkey followed by transplantation of PSC-CMs. This method ensures the establishment of a myocardial infarction model and enables reliable PSC-CM transplantation.
科研通智能强力驱动
Strongly Powered by AbleSci AI