外展
自闭症谱系障碍
自闭症
医学
神经发育障碍
神经科学
心理学
精神科
政治学
法学
作者
Brett D. Dufour,Lilia Albores‐Gallo,José Luna‐Muñoz,Randi J. Hagerman,Amaya Miquelajáuregui,Efraín Buriticá,Wilmar Saldarriaga,Mar Pacheco‐Herrero,Ana Yris Silvestre‐Sosa,Carla A. Mazefsky,Holly Zajac Gastgeb,Julia Kofler,Manuel F. Casanova,Patrick R. Hof,Eric London,Paul J. Hagerman,Verónica Martínez‐Cerdeño
摘要
Abstract Neurodevelopmental disorders (NDDs) are conditions that present with brain dysfunction due to alterations in the processes of brain development. They present with neuropsychiatric, cognitive, and motor symptoms. Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are two of the most common NDDs. Human brain tissue is a scarce resource that is obtained from postmortem donations. In the case of NDDs, specifically autism, the reduced donation rate of brains prevents researchers to investigate its pathology and fine anatomy. The Hispano‐American Brain Bank of Neurodevelopmental Disorders (Banco Hispanoamericano de CE rebros de trastornos del NE urodesarrollo) or CENE is a large‐scale brain bank for neurodevelopmental disorders in Hispano‐America and the US. CENE's objectives are to collect and distribute brains of patients with NDDS, with a focus on ASD and FXS, to perform research, promote education of future scientists, and enhance public awareness about the importance of human tissue availability for scientific research on brain function and disease. CENE has thus far established a bilingual system of nodes and teams in several American countries including California‐US, Pennsylvania‐US, México, Puerto Rico, Colombia, and Dominican Republic. CENE ensures that postmortem NDD samples used in research better match the world's genetic and ethnic diversity. CENE enables and expands NDD brain research worldwide, particularly with respect to ASD and FXS.
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