Preparation of Polyamide 6/CeO2 Composite Nanofibers through Electrospinning for Biomedical Applications

Polyamide 6 (PA6)/CeO 2 composite nanofibers were prepared by electrospinning technique. The morphological, structural, and mechanical properties of the PA6/CeO 2 nanofibers were investigated by using SEM, XRD, Fourier transform-infrared (FT-IR) spectroscopy, and an electronic universal tensile testing machine. SEM images revealed that the nanofibers were well oriented and had good incorporation with CeO 2 , the average diameter of composite fibers first decreases and then increases with the loading of CeO 2 . The crystallinity of fibers decreases after the addition of CeO 2 . The tensile strength of the fibers first increases and then decreases with the increasing concentration of CeO 2 . The proliferation properties of mouse macrophages and osteoblasts on the PA6/CeO 2 nanofibers were analyzed by an in vitro cell compatibility test, the results show that PA6/CeO 2 composite fibers is nontoxic to macrophages and osteoblasts and has good biocompatibility.