化学
间苯二甲酸
油酸
聚合物
配位聚合物
配体(生物化学)
核化学
高分子化学
受体
有机化学
生物化学
聚酯纤维
对苯二甲酸
作者
Ai-Shu Chen,Ping Zhang,Ling Jin,Kunzheng Wang,Jianghong Qu
标识
DOI:10.1080/24701556.2020.1808016
摘要
By using a mixed-ligand approach, a new Co(II)-bearing coordination polymer (CP) with the chemical formula of [{Co(BINDI)0.5(bpa)0.5(H2O)}·4H2O]n (1, H4BINDI = N,N′-bis(5-isophthalic acid)naphthalenediimide, bpa = 1,2-bis(4-pyridyl)ethane) has been synthesized by room temperature self-assembly and structurally characterized successfully. Furthermore, a process of sonochemistry with oleic acid treatment at 453 K was used to produce the nanostructure 1 (denoted as nano 1 hereafter). The inhibitory effect of nano 1 on cervical cancer cells was determined. Firstly, the CCK-8 assay was performed. The Reverse Transcription Polymerase Chain Reaction (RT-PCR) assay was performed and the relative expression levels of miR-16-1 were determined. Then, the western blotting detection was conducted and the Bcl-2 expression level after nano 1 treatment was evaluated.
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