Recommendations for the management of symptomatic Clostridium difficile infection (CDI).

Risk factors for CDI progression. In addition to factors enumerated above, advanced age of patient (>64 years old) constitutes the most important risk factor for symptomatic Clostridium difficile infection and its severe and complicated course. Furthermore, other important risk factors include duration of hospitalization and contact with Clostridium difficile-infected persons during stay in hospital, use of inhibitors–H2, proton pump inhibitors and HIV infection.