The Postprandial Glycemic Excursions in Gestational Diabetes Mellitus Patients Revealed by Continuous Glucose Monitoring System

Objective:To observe postprandial glycemic excursions in gestational diabetes mellitus(GDM) patients using the Continuous Glucose Monitoring System(CGMS).Methods:Fifteen pregnant women were chosen to be evaluated with a 1 h/50 g glucose challenge test and a 3 h/100 g oral glucose tolerance test.The fifteen GDM patients using the CGMS were evaluated for 72 consecutive hours.The postprandial glycemic data taken from 0～180 by 30 minutes interval after each meal was analyzed.Results:There was a significant increment of postprandial glycemea after breakfast than lunch or dinner.Preprandial glycemic data revealed a vale in one day(5.15±0.01)mmol/L.Within postprandial 3 hours,the average of glycemic value was 5.96±1.63 mmol/L.There were significant excursions from the vale to peak of glycemic data from 3.36±0.47 mmol/L to 9.58±1.38 mmol/L.In GDM women,the postprandial 2 hours glycemic data was ≥7.2 mmol/L(7 cases),≥11.1 mmol/L(one case),and ≤3.9 mmol/L(4 cases).Conclusions:CGMS can help observe the postprandial glycemic excursions in GDM,and contribute to the decision of therapy approach:diet,exercise or drug treatment during pregnancy.