Effectiveness of combined arthrocentesis with platelet-rich plasma, platelet rich-fibrin, hyaluronic acid, corticosteroids and non-steroidal anti-inflammatory drugs in temporomandibular joint osteoarthritis: a systematic review and meta-analysis of randomized clinical trials

Combined arthrocentesis techniques show significant improvements in maximum mouth opening at six and twelve months and in pain at twelve months pos-treatment. However, the lack of protocol development and the scarcity of similar studies highlight the heterogeneity of the results.