生物
骨骼肌
细胞生物学
基因
病毒学
遗传学
解剖
作者
Devin Gibbs,April D. Pyle
出处
期刊:Cell
[Elsevier]
日期:2023-05-01
卷期号:186 (10): 2041-2043
标识
DOI:10.1016/j.cell.2023.04.021
摘要
Viruses and multinucleated cells rely on fusogens to facilitate the fusion of their membranes. In this issue of Cell, Millay and colleagues demonstrate that replacing viral fusogens with mammalian skeletal muscle fusogens leads to the specific transduction of skeletal muscle and the ability to deliver gene therapy constructs in a therapeutically relevant muscle disease.
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