The Spleen in Local and Systemic Regulation of Immunity

(Immunity 39, 806–818; November 14, 2013) In the above Review article, the authors referred to an image resource hosted on the Immunity website in the legend of Figure 1. The image resource is no longer available. The journal apologizes for the inconvenience. The Spleen in Local and Systemic Regulation of ImmunityBronte et al.ImmunityNovember 14, 2013In BriefThe spleen is the main filter for blood-borne pathogens and antigens, as well as a key organ for iron metabolism and erythrocyte homeostasis. Also, immune and hematopoietic functions have been recently unveiled for the mouse spleen, suggesting additional roles for this secondary lymphoid organ. Here we discuss the integration of the spleen in the regulation of immune responses locally and in the whole body and present the relevance of findings for our understanding of inflammatory and degenerative diseases and their treatments. Full-Text PDF Open Archive