光热治疗
姜黄素
单线态氧
生物相容性
光动力疗法
涂层
材料科学
钛
抗菌活性
抗菌剂
化学
纳米技术
核化学
氧气
细菌
有机化学
冶金
生物化学
生物
遗传学
作者
Qing Guo,Peiyuan Li,Ying Zhang,Hongjun Yan,Qiuyan Yan,Rixiang Su,Wei Su
摘要
Combined photothermal therapy (PTT) and photodynamic therapy (PDT) has emerged as a novel and effective antibacterial strategy. In order to endow titanium (Ti) with antibacterial properties, the Ti-PDA-Cur composite was prepared using the excellent adhesion properties of polydopamine (PDA) to load curcumin (Cur) on the surface of Ti. The Ti-PDA-Cur coating can produce singlet oxygen (1 O2 ) and heat under 405 + 808 nm light irradiation, which can effectively kill Staphylococcus aureus and Escherichia coli. Moreover, the cytotoxicity and hemolysis rate of Ti-PDA-Cur were low, indicating its good biocompatibility. Therefore, this study provided a new strategy for the development of new Ti implants.
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