前交叉韧带
骨形态发生蛋白
医学
外科
前交叉韧带重建术
固定(群体遗传学)
骨髓抽出物
骨髓
生物
病理
生物化学
环境卫生
人口
基因
作者
Christopher J. McMellen,Margaret A. Sinkler,Jacob G. Calcei,Taylor E. Hobson,Michael R. Karns,James E. Voos
标识
DOI:10.2106/jbjs.22.01321
摘要
➤ Both mechanical and biological factors can contribute to bone loss and tunnel widening following primary anterior cruciate ligament (ACL) reconstruction. ➤ Revision ACL surgery success is dependent on graft position, fixation, and biological incorporation. ➤ Both 1-stage and 2-stage revision ACL reconstructions can be successful in correctly indicated patients. ➤ Potential future solutions may involve the incorporation of biological agents to enhance revision ACL surgery, including the use of bone marrow aspirate concentrate, platelet-rich plasma, and bone morphogenetic protein-2.
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