Dansylprotamine, a fluorometric reagent for determination of nucleic acids.

DNA and RNA were found to enhance the fluorescence of dansylprotamine. This finding was applied to microdetermination of nucleic acids. This method is valid for samples containing 0.1 - 5.0 μg/ml of nucleic acids. Nucleic acids and dansylprotamine were found to bind each other through both electrostatic and hydrophobic interaction.