医学
经皮冠状动脉介入治疗
心脏病学
内科学
血小板
旁路移植
动脉
血小板活化
心肌梗塞
作者
Lisa Groß,Dirk Sibbing
标识
DOI:10.1016/j.iccl.2016.08.011
摘要
There is interindividual variability in the pharmacodynamic response to antiplatelet medications. High on-treatment platelet reactivity, reflecting a failure to achieve adequate platelet inhibition, is associated with a higher risk for thrombotic events. Low on-treatment platelet reactivity, or an enhanced response to antiplatelet medications, has been linked to a higher risk for bleeding. There is evidence for the prognostic value of platelet function testing for risk prediction. This review presents the current evidence regarding platelet function testing in patients undergoing percutaneous cardiac intervention and coronary artery bypass grafting. The possible role of platelet function testing for individualized antiplatelet treatment is highlighted.
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