调解人
RNA聚合酶Ⅱ
染色质
细胞生物学
抄写(语言学)
转录因子
计算生物学
生物
遗传学
基因
基因表达
发起人
语言学
哲学
作者
E. V. Putlyaev,Airat Ibragimov,Л. А. Лебедева,Pavel Georgiev,Yulii V. Shidlovskii
出处
期刊:Biokhimiya
[Pleiades Publishing]
日期:2018-04-01
卷期号:83 (4): 423-436
被引量:10
标识
DOI:10.1134/s0006297918040132
摘要
Mediator is a key factor in the regulation of expression of RNA polymerase II-transcribed genes. Recent studies have shown that Mediator acts as a coordinator of transcription activation and participates in maintaining chromatin architecture in the cell nucleus. In this review, we present current concepts on the structure and functions of Mediator.
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