Nematode sperm locomotion

The simplicity and specialization of the amoeboid motility of nematode sperm can give intriguing insights into the molecular mechanisms underlying movement in more conventional actin-based systems. Amoeboid motility in nematode sperm is based on their major sperm protein. Advances over the past year in understanding the assembly of this protein in vivo and in vitro have underlined the importance of vectorial assembly and filament bundling. In this system, it is possible that these two properties may be sufficient to generate motility that closely resembles that seen in conventional actin-based systems.